Common Indications for Liver Transplant
- Cholestatic Disorders:
- Primary & secondary biliary cirrhosis
- Primary sclerosing cholangitis
- Biliary atresia
- Familial cholestatic syndromes
- Hepatocellular Disorders:
- Chronic autoimmune hepatitis
- Chronic viral hepatitis (B, C)
- Alcoholic liver disease
- Chronic drug induced liver disease
- Vascular Outflow Disease:
- Budd-Chiari syndrom
- Veno-occlusive disease
- Hepatocellular Carcinoma
Absolute & Relative Contraindications
The list of absolute and relative contraindications for Liver Transplant is continually evolving as our experience with certain pre-existing conditions and diseases grows.
At present, the only absolute contraindications for Liver Transplant appear to be:
- Active sepsis outside the hepatobiliary system
- Advanced cardiopulmonary disease or acute hemodynamic compromise at the time of transplant, accompanied by compromise or failure of one or more vital organs
- Presence of malignancy metastatic or extrahepatic
- AIDS
Relative contraindications include the following:
- Age great than 72
- Portal vein thrombosis with mesenteric vein thrombosis
- Extrahepatic cholangiocarcinoma
- HIV positivity – considered on case-by-case basis
- Active alcohol or drug abuse
Candidacy for Combined Liver/Kidney Transplant:
We do perform combined liver and kidney transplants in selected patients. Liver transplant candidates with a CrCl of ≤ 40 for ≥ 6 weeks whose renal failure is not expected to improve after transplant will be considered for a possible kidney transplant. These patients, along with all liver transplant candidates on renal replacement therapy, will be evaluated by the transplant nephrology service.
Transplant Hotline
1-800-643-1635
