Calciphylaxis is a syndrome of vascular calcification and skin necrosis. It is seen almost exclusively in patients with end stage renal disease. It results in chronic non-healing wounds and requires parathyroidectomy and hyperbaric therapy. Calciphylaxis is a rare but serious disease.
Patients with this condition usually have experienced kidney failure and have undergone kidney dialysis. The disease produces purple or red lesions typically located on the lower extremities or abdomen. The lesions can then develop thick, dark crusts and open skin ulcers.