Scleroderma is a diffuse connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs.
"¢ Blanching, blueness, or redness of fingers and toes in response to heat and cold (Raynaud's phenomenon)
"¢ Pain, stiffness, and swelling of fingers and joints
"¢ Skin thickening and shiny hands and forearm
"¢ Skin is hard