Acute cytomegalovirus (CMV) infection is a condition caused by a member of the herpesvirus family. In most people with a normal immune system, CMV infection does not cause any symptoms. But, some people with this infection develop a "mononucleosis syndrome." Symptoms When first infected (primary CMV), some adults may have symptoms similar to mononucleosis. Signs and symptoms of primary CMV include:
- Fatigue
- Weakness
- Night sweats
- Prolonged fever
- Swollen glands or sore throat, or both
- Loss of appetite or weight loss, or both
- Muscle aches or joint pain or stiffness
- General feeling of illness, discomfort or uneasiness

