Indications & Contraindications for Heart Transplant Surgery

Who Can Have a Heart Transplant?

Patients with end-stage cardiac disease including but not limited to the following will be considered for heart transplant:

  • Cardiomyopathy (with class II or IV congestive heart failure)
  • Class IV angina (on medical therapy not amenable to revascularization despite evidence of ischemia on stress test)
  • Non-obstructive hypertrophic heart disease
  • Severe decompensated inoperable valvular heart disease
  • Transthyretin related (TTR) amyloidosis involving the heart (with no other end organ damage)
  • Congenital heart disease (without irreversible pulmonary hypertension)
  • Any other cardiac abnormalities that severely limit normal function and/or have a mortality risk of greater than 50% at two years

Upon re-evaluation, patients with the following potentially reversible or treated comorbidities may be considered for transplant:

  • Cancer
  • Morbid obesity
  • Uncontrolled diabetes mellitus
  • Renal failure
  • Tobacco/marijuana use
  • Pharmacologically irreversible pulmonary hypertension

Until transplant approval, patients may consider the use of mechanical circulatory support.

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