Indications/Contraindications

Indications

Common indications for liver transplant include end-stage liver disease and cirrhosis caused by

  • Viruses
  • Alcohol and/or drugs
  • Obesity
  • Genetic disorders
  • and/or
  • Liver cancers

Absolute and Relative Contraindications

The list of absolute and relative contraindications for liver transplant is continually evolving as our experience with certain pre-existing conditions and diseases grows.

At present, the only absolute contraindications for liver transplant appear to be:

  • Active sepsis
  • Advanced cardiopulmonary disease
  • Failure of one or more organs
  • Malignancy (metastatic or extrahepatic)
  • AIDS

Relative contraindications include:

  • Age greater than 72 years old
  • Portal vein thrombosis with mesenteric vein thrombosis
  • Extrahepatic cholangiocarcinoma
  • HIV positivity (considered on a case-by-case basis)
  • Active alcohol or drug abuse

Candidacy for Combined Liver/Kidney Transplant:

We perform combined liver and kidney transplants in selected patients. Liver transplant candidates with a CrCl of 40 for six weeks whose kidney failure is not expected to improve after transplant will be considered for a possible kidney transplant. These patients, along with all liver transplant candidates on dialysis, will be evaluated by the transplant nephrology service.

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